Reflecting recent investigations neurotrophins and the neural crest is dedicated to the roles neurotrophins play in neural crest cell differentiation and in the survival of neural crest derivatives. Neurotrophin 3 nt 3 promotes the survival and induces neurite outgrowth from a subset of neural crest nc and placode derived neurons we now report that this growth factor regulates the proliferation of cultured nc progenitor cells grown in a serum free defined medium. Focuses on the roles neurotrophins play in neural crest cell differentiation and in the survival of neural crest derivatives this book correlates in vitro data with results obtained from knock out mice with targeted neurotrophin or receptor deletions to determine the fidelity and usefulness of various experimental culture systems. The neural crest is a migratory population of cells that gives rise to a wide range of cell types in the peripheral nervous system of vertebrate embryos. Crc press 1998 hardcover brand new original us edition for multiple orders and expedite orders we use fedex ups dhl service receive fast within 3 5 business days
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